Strokes shift emission spectroscopy for detection of disease...

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G01N 21/63 (2006.01) A61B 1/04 (2006.01) A61B 1/07 (2006.01) G01N 21/31 (2006.01) G01N 33/483 (2006.01)

Patent

CA 2514741

The Stokes shift emission spectra were measured for various samples, including tissues containing photoactive bio-molecules such as tryptophan, elastin, collagen, NADH and flavin. This new approach allows for the extraction of new information not easily obtained from the extraction of new information not easily obtained from the excitation and/ or fluorescence spectra of the same samples. For example, Stokes shift spectroscopy of tissue samples can detect disease states in humans and animals.

L'invention concerne des spectres d'émission de décalage Stokes mesurés dans des échantillons variés comprenant des tissus contenant des biomolécules photoactives, notamment du tryptophane, de l'élastine, du collagène, du NADH et de la flavine. Cette nouvelle approche permet l'extraction de nouvelles informations n'étant pas facilement obtenues à partir des spectres d'excitation et/ou de fluorescence de ces même échantillons. Par exemple, une spectroscopie de décalage Stokes d'échantillons de tissu peut permettre de détecter des états pathologiques chez les humains et chez les animaux.

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