Structural and functional conservation of the c. elegans...

Details Structural and functional conservation of the c. elegans... Structural and functional conservation of the c. elegans...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01K 67/027 (2006.01) A01K 67/033 (2006.01) A61K 35/00 (2006.01) C07K 14/435 (2006.01)

Patent

CA 2268749

The present invention relates to a clk-1 gene which has a function at the level of cellular physiology involved in developmental rate and longevity, wherein clk-1 mutants have a longer life and a altered cellular metabolism relative to the wild-type. There is also provided a method for the diagnosis and/or prognosis of cancer in a patient, which comprises the steps of: a) obtaining a tissue sample from the patient; b) analyzing DNA of the obtained tissue sample of step a) to determine if the human clk-1 gene is altered, wherein alteration of the human clk-1 gene is indicative of cancer. There is also provided a method of treatment of pathological conditions causing slowdown of physiological rate of tissue and/or organ in a patient.

La présente invention se rapporte à un gène clk-1 ayant une fonction au plan de la physiologie cellulaire en rapport avec le rythme de développement et la longévité; l'invention se rapporte également à des mutants de clk-1 vivant plus longtemps et possédant un métabolisme cellulaire modifié par rapport au type sauvage. En outre, l'invention concerne une méthode de diagnostic et/ou de pronostic du cancer chez un patient; ladite méthode comprend deux stages qui consistent (a) à obtenir un échantillon du tissu d'un patient et (b) à analyser l'ADN de l'échantillon de tissu obtenu au stade (a) pour déterminer si le gène humain clk-1 est modifié, la modification du gène humain clk-1 indiquant la présence d'un cancer. L'invention propose finalement une méthode de traitement d'états pathologiques provoquant un ralentissement du rythme physiologique d'un tissu et/ou d'un organe chez un patient.

Affiliated with

Also associated with

Rating

Structural and functional conservation of the c. elegans... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Structural and functional conservation of the c. elegans..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Structural and functional conservation of the c. elegans... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2033033