Structure-based screening techniques for drug discovery

Details Structure-based screening techniques for drug discovery Structure-based screening techniques for drug discovery

G - Physics

01

N

G01N 33/50 (2006.01) C07K 14/71 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2362541

The invention relates to novel non-naturally occurring cell surface receptor analogs, ligand analogs and nucleic acids encoding them. The invention further provides methods for screening of ligand analogs and bioactive agents capable of modulating the signaling activity of a non-naturally occurring cell surface receptor analog or capable of binding to a non-naturally occurring cell surface receptor analog.

L'invention concerne de nouveaux analogues de récepteur de surface cellulaire d'origine non naturelle, des analogues de ligand, et des acides nucléiques codant pour ceux-ci. L'invention concerne également des techniques de criblage d'analogues de ligand et d'agents bioactifs capables de moduler l'activité de signalisation d'un analogue de récepteur de surface cellulaire d'origine non naturelle ou de se lier audits analogues de récepteur de surface cellulaire d'origine non naturelle.

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