C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2331919
The present invention relates to an antisense nucleic acid molecule comprising a first region and a second region, both of which are complementary to a target nucleic acid molecule, and wherein the first region is available for hybridisation and the second region is temporarily masked. The antisense molecules of the invention display increased specificity and stability of binding.
Cette invention a trait à une molécule d'acide nucléique antisens comprenant une première et une seconde région qui, toutes deux, sont complémentaires d'une molécule d'acide nucléique, la première région étant disponible aux fins d'une hybridation et la seconde région étant provisoirement masquée. Ces molécules antisens font montre d'une spécificité et d'une stabilité de fixation accrues.
Rabbitts Terence
Stocks Martin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Medical Research Council
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