Styrene derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 225/32 (2006.01) A61K 31/12 (2006.01) A61K 31/165 (2006.01) A61K 31/275 (2006.01) C07C 45/45 (2006.01) C07C 45/54 (2006.01) C07C 45/56 (2006.01) C07C 45/71 (2006.01) C07C 47/575 (2006.01) C07C 49/835 (2006.01) C07C 49/84 (2006.01) C07C 235/38 (2006.01) C07C 255/40 (2006.01) C07C 255/41 (2006.01) C07C 255/60 (2006.01) C07C 317/32 (2006.01) C07C 317/46 (2006.01) C07C 323/41 (2006.01)

Patent

CA 2080554

- 89 - Abstract of Disclosure: Styrene derivatives of the following general formula (I): Image (I) [R1: cyano group, etc. R2: Image (Z is hydrogen atom, halogen atom, etc.), etc., R3: hydrogen atom, hydroxy group, etc., R4, R8: hydrogen atom, halogen atom, nitro group, etc., R5, R7: hydrogen atom, hydroxy group, halogen atom, cyano group, C1 - C5 alkoxy group, C1 - C5 alkyl group, etc., R6: hydroxy group, etc.] or pharmaceutically acceptable salts thereof. A pharmaceutical composition useful as anticancer agent, which comprises the above compound as an essential component, is also provided.

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