A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/277 (2006.01) A61P 15/06 (2006.01)
Patent
CA 2463133
The invention relates to the use of organic compounds, styryl acrylonitrile compounds to promote myelopoiesis. These compounds thefore may be used to treat a subject suffering from neutropenia and other conditions which would benefit from increased myelopoieses. Moreover, the compounds may be used to treat hematopoietic cells ex-vivo to promote myelopoiesis and therefore may be used advantageously in bone marrow or peripheral blood stem cell transplant.
L'invention concerne des composés organiques - des composés styryl acrylonitrile - utilisés pour favoriser la myélopoïèse. Ces composés peuvent être utilisés pour traiter un sujet souffrant de neutropénie ou d'autres affections contre lesquelles une myélopoïèse accrue est bénéfique. Les composés selon l'invention peuvent également être utilisés pour traiter des cellules hématopoïétiques ex-vivo pour favoriser la myélopoïèse. Ces composés peuvent donc être utilisés avantageusement dans les greffes de moelle osseuse ou les greffes de cellules souches sanguines périphériques.
Demin Peter M.
Freywald Andrew
Grunberger Thomas
Roifman Chaim M.
Rounova Olga B.
Gowling Lafleur Henderson Llp
The Hospital For Sick Children
LandOfFree
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