Styrylamidines

Details Styrylamidines Styrylamidines

C - Chemistry, Metallurgy

07

C

260/544.3, 260/5

C07C 123/00 (1980.01) C07C 143/78 (1980.01)

Patent

CA 1071651

Abstract of the Disclosure Styrylamidines are prepared by treating styrylsulfonylamidines with base. The styrylamidines of the invention are effective in the prevention of aggregation of blood platelets and as analgesiics. The styrylsulfonylanidines of the invention which serve as precursors to the styrylamidines also have analgesic properties. Illustrative of the styrylanidines of the present invention are 4-amino-N-(4-aminostyryl)- benzemidite and N-(3,4-dichlorostyryl)acetamidine. An example of a styrylsulfonylamidine is N-(styryl)sulfonylacetamidine.

221801

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