Subcutaneous implants having limited initial release of the...

Details Subcutaneous implants having limited initial release of the... Subcutaneous implants having limited initial release of the...

A - Human Necessities

61

K

A61K 9/22 (2006.01)

Patent

CA 2530120

Subcutaneous implants having limited initial release of the active principle and subsequent linearly varying extended release thereof consisting of: a core (i) comprising an active principle dispersed in a polymeric matrix of polylactic-glycolic acid (PLGA) copolymer, a coating in film form (ii), comprising as the main component a lactic-glycolic acid copolymer, and the relative processes for preparing said implants.

L'invention concerne des implants sous-cutanés à libération initiale de principe actif contrôlée, puis à libération prolongée à variation linéaire comprenant: un noyau i) renfermant un principe actif dispersé dans une matrice polymère d'un copolymère d'acide polylactique-glycolique (PLGA), et un enrobage sous forme de film ii) comprenant comme composant principal un copolymère d'acide polylactique-glycolique. L'invention concerne également des procédés permettant de préparer lesdits implants.

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