Sublingual or buccal pharmaceutical composition

Details Sublingual or buccal pharmaceutical composition Sublingual or buccal pharmaceutical composition

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 31/407 (2006.01)

Patent

CA 2182981

The invention relates to a sublingual or buccal pharmaceutical composition comprising trans-5-chloro-2-methyl-2,3,3a, 12b-tetrahydro- 1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole or a pharmaceutically acceptable salt thereof, and, pharmaceutically acceptable auxiliaries suitable for use in sublingual or buccal compositions, and the use thereof for the manufacture of a sublingual or buccal pharmaceutical composition for the treatment of mental disorders, such as psychosis and schizophrenia.

L'invention se rapporte à une composition pharmaceutique sublinguale ou buccale comprenant le trans-5-chloro-2-méthyl-2,3,3a,12b-tétrahydro-1H-dibenz[2,3:6,7]oxépino[4,5-c]pyrrole ou un sel de celui-ci pharmacologiquement acceptable, ainsi qu'aux excipients pharmacologiquement acceptables appropriés aux compositions sublinguales ou buccales; l'invention se rapporte également à l'utilisation de ce composé pour la fabrication d'une composition pharmaceutique sublinguale ou buccale destinée au traitement de troubles mentaux, notamment la psychose et la schizophrénie.

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