Sublingual spray formulation comprising dihydroartemesinin

Details Sublingual spray formulation comprising dihydroartemesinin Sublingual spray formulation comprising dihydroartemesinin

A - Human Necessities

61

K

A61K 31/335 (2006.01) A61K 9/12 (2006.01)

Patent

CA 2756925

The invention provides pharmaceutical compositions for the treatment of neoplastic diseases, fluke infestations and Lyme disease, comprising compounds capable of providing dihydroartemesinin and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compo-sitions.

L'invention porte sur des compositions pharmaceutiques pour le traitement de maladies néoplasiques, d'infestations par la douve et de la maladie de Lyme, comprenant des composés capable de fournir de la dihydroartémésinine et un triglycéride à chaîne moyenne formulées pour une administration transmucosale, sublinguale, buccale ou nasale, notamment par pulvérisation. L'invention porte également sur des dispositifs d'administration contenant les compositions.

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