Submucosa gel compositions

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/00 (2006.01) A61K 35/38 (2006.01) C12S 3/24 (2006.01)

Patent

CA 2321117

A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.

L'invention concerne une composition comprenant de la sous-muqueuse qui a subi une transformation enzymatique et provient d'un vertébré à sang chaud, ainsi qu'un procédé de préparation de cette composition. Plus particulièrement, la sous-muqueuse est transformée par des enzymes et gélifiée de manière à donner une matrice de gel qui garde la forme qu'on lui donne et qui permet d'induire une prolifération et une croissance cellulaires in vivo et in vitro.

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