C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/735 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2547126
The invention relates to novel immunogens carrying conformationally discriminating epitopes (CDEs) and to immunization methods for producing antibodies that specifically recognize proteins with very closely related homologues. In particular, the invention relates to antibodies which are specific for either Fc.gamma.Rllb or Fc.gamma.Rlla.
L'invention concerne de nouveaux immunogènes portant des épitopes à conformation discriminante (CDE) et des procédés d'immunisation permettant de produire des anticorps qui reconnaissent de façon spécifique des protéines avec des homologues très étroitement liés. L'invention concerne en particulier des anticorps spécifiques de Fc?RIIb ou Fc?RIIa.
Cabrele Chiara
Huber Robert
Jacob Uwe
Moroder Luis
Sondermann Peter
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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