Substance p and analogs thereof as an immunogenic...

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) A61K 39/145 (2006.01) A61P 31/12 (2006.01) A61P 31/16 (2006.01) A61P 37/04 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2675753

Substance P and bioactive analogs thereof can be used as an adjuvant with immunogenic compositions to enhance the immunizing properties of the immunogenic compositions. In some embodiments, the amount of antigen needed in each dose of immunogenic composition is decreased due to the adjuvant activity of the substance P analogs.

L'invention concerne une substance P et ses analogues bioactifs qui peuvent être utilisés en tant qu'adjuvant avec des compositions immunogènes pour améliorer les propriétés d'immunisation des compositions immunogènes. Selon certains modes de réalisation, la quantité d'antigène nécessaire dans chaque dose de composition immunogène est diminuée en raison de l'activité d'adjuvant des analogues de la substance P.

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