Substances for preventing and treating autoimmune diseases

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 48/00 (2006.01) C12N 15/87 (2006.01) C12N 15/12 (2006.01) C12N 15/60 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2494888

A substance for preventing, delaying the onset of, or treating one or more than one autoimmune disease, the substance comprising a polynucleotide construct comprising a polynucleotide sequence encoding the pro-apoptotic protein BAX and encoding one or more than one autoantigen for the autoimmune disease. A method for preventing, delaying the onset of or treating an autoimmune disease in a patient comprising selecting a patient who is susceptible to developing the autoimmune disease, who is developing the autoimmune disease or who has the autoimmune disease and administering to the patient one or more than one dose of a polynucleotide construct comprising a polynucleotide sequence encoding the pro-apoptotic protein BAX and encoding one or more than one autoantigen for an autoimmune disease, or comprising a polynucleotide sequence encoding the adenoviral protein E3-GP19k, or comprising a polynucleotide sequence encoding .DELTA.BCL-2.

L'invention concerne une substance pour prévenir, traiter une ou plusieurs maladies auto-immunes ou en retarder l'apparition. Ladite substance comprend une construction polynucléotidique comprenant une séquence polynucléotidique codant pour la protéine pro-apoptotique BAX et codant pour au moins un auto-antigène pour la maladie auto-immune. L'invention porte également sur un procédé de prévention, de traitement d'une maladie auto-immune ou de retardement de son apparition chez un patient, qui consiste à sélectionner un patient susceptible de développer la maladie auto-immune, en train de développer la maladie auto-immune ou souffrant de ladite maladie, et à administrer au patient au moins une dose d'une construction polynucléotidique comprenant une séquence polynucléotidique codant pour la protéine pro-apoptotique BAX et codant pour au moins un antigène pour une maladie auto-immune, ou comprenant une séquence polynucléotidique codant pour la protéine adénovirale E3-GP19k ou comprenant une séquence polynucléotidique codant pour .DELTA.BCL-2.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Substances for preventing and treating autoimmune diseases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substances for preventing and treating autoimmune diseases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substances for preventing and treating autoimmune diseases will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1603336

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.