Substances having antiobese and visceral fat-reducing...

A - Human Necessities – 61 – K

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A61K 31/20 (2006.01) A23K 1/16 (2006.01) A23L 1/29 (2006.01) A23L 1/30 (2006.01) A61K 35/60 (2006.01) C07C 69/587 (2006.01) C07D 307/46 (2006.01) C07D 307/54 (2006.01)

Patent

CA 2342218

Substances containing coupling isomerized highly unsaturated fatty acids and/or derivatives thereof which have a function of specifically promoting the uncoupling respiration of mitochondria (MC) and proton leak in the MC membrane in cells of major nonshivering thermogenesis (nST)-producing tissues, skeletal muscle, white adipose tissue (WAT), brown adipose tissue (BAT), etc. of mammals including humans and birds; antiobese (inhibiting the accumulation of visceral fat (in particular, mesenteric fat))/visceral (in particular, mesenteric) fat-reducing agents containing the above substances as the active ingredient; foods having antiobese (inhibiting the accumulation of visceral fat (in particular, mesenteric fat))/visceral (in particular, mesenteric) fat- reducing functions which contain the above substances as the active ingredient; and feeds having antiobese (inhibiting the accumulation of visceral fat (in particular, mesenteric fat))/visceral (in particular, mesenteric) fat-reducing functions which contain the above substances as the active ingredient.

L'invention concerne des substances contenant des acides gras de couplage isomérisés et hautement insaturés et/ou leurs dérivés ayant la fonction de promouvoir spécifiquement le découplement de la respiration des mitochondries (MC) et des fuites protoniques dans la membrane MC dans des cellules de tissus produisant une thermogenèse sans tremblements majeure (nST), les muscles squelettiques, les tissus adipeux blancs (WAT), les tissus adipeux bruns (BAT), etc. de mammifères comprenant les humains et les oiseaux. L'invention concerne également des agents réduisant les graisses, anti-obèses (inhibant l'accumulation de graisses viscérales, en particulier de graisses viscérales, graisses mésentériques/viscérales), notamment mésentériques, lesdits agents contenant les substances précitées comme ingrédients actifs, des produits alimentaires à fonctions réduisant les graisses, anti-obèses (inhibant l'accumulation de graisses viscérales, en particulier de graisses viscérales, graisses mésentériques/viscérales), notamment mésentériques, renfermant les substances précitées comme ingrédients actifs, et des aliments pour animaux à fonctions réduisant les graisses, anti-obèses (inhibant l'accumulation de graisses viscérales, graisses mésentériques/viscérales), notamment mésentériques, renfermant les substances précitées comme ingrédients actifs.

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