C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/109, 167/187
C07D 501/22 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/02 (2006.01) C07D 501/12 (2006.01)
Patent
CA 1339213
The invention relates to a substantially anhydrous crystalline cefadroxil having a water content between about 0.8% and 3.9%. Such cefadroxil is obtained slurrying a cefadroxil solvate of dimethylacetamide, or of N-methyl-2-pyrrolidone or of monomethyl-formamide, with isopropyl alcohol containing either from about 2% to 4% of water of from about 0.1% to 4% of water and from 0% to about 60% of methanol, at a temperature in the range of about +45°C to +55°C and than filtering the desired cefadroxil so obtained.
555491
Rifar S.r.l.
Robic
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