C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 11/06 (2006.01)
Patent
CA 2566213
The present invention is directed to the substantially pure compound of formula (A), or pharmaceutically acceptable salt, or solvate of said compound; to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula (A), and a pharmaceutically acceptable carrier; and the use of a compound of formula (A) having activity as an inhibitor, preferably a selective inhibitor, of IkB (IKK), particularly IKK-2, and methods related thereto.
La présente invention est destinée au composé substantiellement pur de formule (A) ou à un sel pharmaceutiquement acceptable ou un solvat dudit composé ; à une composition pharmaceutique comprenant la quantité pharmaceutiquement efficace du composé de formule (A) et un vecteur pharmaceutiquement acceptable ; l'utilisation d'un composé de formule (A) ayant une activité d'inhibiteur, de préférence un inhibiteur sélectif, de IkB (IKK), en particulier IKK-2 et les méthodes liées à cela.
Aldous David J.
Cox Paul Joseph
Haddad El-Bdaoui
Ritzeler Olaf
Aventis Pharmaceuticals Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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