Substantially pure fluorescein

Details Substantially pure fluorescein Substantially pure fluorescein

C - Chemistry, Metallurgy

07

D

C07D 493/10 (2006.01)

Patent

CA 2671860

The present invention is directed to an improved process for producing substantially pure fluorescein, as well as to substantially pure fluorescein compositions prepared by the process. The invention is particularly directed to the provision of pharmaceutical compositions for use in angiography. The substantially pure fluorescein produced by the process of the present invention is low in color, low in sodium chloride content, and substantially free of pyridine.

La présente invention concerne un procédé amélioré permettant de produire de la fluorescéine sensiblement pure ainsi que des compositions à base de fluorescéine sensiblement pure préparées au moyen de ce procédé. L'invention concerne particulièrement le fait de fournir des compositions pharmaceutiques destinées à être utilisées en angiographie. La fluorescéine sensiblement pure produite au moyen du procédé de la présente invention est peu colorée, pauvre en chlorure de sodium et sensiblement exempte de pyridine.

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