Substantially purified tumor growth inhibitory factor (tif)

Details Substantially purified tumor growth inhibitory factor (tif) Substantially purified tumor growth inhibitory factor (tif)

C - Chemistry, Metallurgy

12

P

167/104, 195/128

C12P 21/00 (2006.01) A61K 35/12 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1311704

Substantially Purified Tumor Growth Inhibitory Factor (TIF) Abstract The invention relates to a substantially purified substance having the property of inhibiting tumor cell growth without inhibiting the growth of normal cells or having an antiviral effect. The substance is characterized by the following characteristics: (a) having a molecular weight ranging from about 3,500 to 45,000 daltons; (b) being stable at 56°C upon exposure for about 30 minutes; (c) having an isoelectric point ranging from pI 4-8; and, (d) eluting on high pressure liquid chromatography at about 10-35% of 2-propanol or about 25-50% of acetonitrile present.

479630

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