Substitute for human blood and method of making the same

Details Substitute for human blood and method of making the same Substitute for human blood and method of making the same

A - Human Necessities

61

K

167/114

A61K 35/14 (2006.01) A61K 37/02 (1985.01) A61K 37/12 (1985.01)

Patent

CA 1253801

ABSTRACT The method of this invention yields a two phase liquid aqueous system which replicates the two phase heterogeneous physicochemical system of naturally occurring whole human blood. The method produces a composition of matter which comprises a whole blood substitute when polymerized hemoglobin ox pyridoxylated- polymerized hemoglobin, and preferably, other specific additives are incorporated. When said blood substitute is processed further, a microencapsulated composition with time release characteristics that can transport oxygen is produced. The invention overcomes the obstacles that have prevented the use of modified hemoglobins like pyridoxylated-polymerized hemoglobin in the preparation of oxygen transport systems.

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