Substituted 1,3,4-thiadiazolinones, processes for their...

C - Chemistry – Metallurgy – 07 – D

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C07D 285/125 (2006.01) A61K 31/425 (2006.01) C07C 337/02 (2006.01) C07D 285/13 (2006.01) C07D 317/46 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2026700

ABSTRACT OF THE DISCLOSURE Substituted 1,3,4-thiadiazolinones of the formula (I), Image (I) in which X represents O or S, R1 represents hydrogen, alkyl, alkoxy, alkylthio, halogen, halogenoalkyl, halogenoalkoxy or halogenoalkylthio, R2 represents one or more identical or different radicals from the series comprising hydrogen, alkyl, alkoxy, alkylthio, halogenoalkyl, halo- genoalkoxy, halogenoalkylthio, alkylenedioxy, halogenoalkylenedioxy, halogen, CN, NO2, NH2, alkylamino, dialkylamino, alkylcarbonyl, carb- alkoxy, alkylsulphonyl, arylsulphonyl, sulph- amoyl, alkylsulphamoyl, dialkylsulphamoyl, aryl, aryloxy and arylthio, each of which can, in turn, be substituted as well, and R3 represents alkyl, alkenyl or alkynyl, each of which can optionally be substituted, with the exception of the compound 5-methylmercapto- 3-phenyl-1,3,4-thiadiazol-2-(3H)-one, are disclosed as being useful to combat endoparasites, Compositions containing these compounds, process for preparing them, and novel intermediates are also disclosed.

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