Substituted 1,3-diaminopropanes

Details Substituted 1,3-diaminopropanes Substituted 1,3-diaminopropanes

C - Chemistry, Metallurgy

07

C

260/251, 260/547

C07C 275/28 (2006.01) C07C 273/18 (2006.01) C07D 239/04 (2006.01)

Patent

CA 2020189

ABSTRACT SUBSTITUTED 1,3-DIAMINOPROPANES N'-Acyl-N-alkyl-1,3-diaminopropanes of formula R1CONH(CH2)3NHR2 where R1 is R- or RNH where R is a substituted or unsubstituted hydrocarbon group and R2 is alkyl) are prepared by selectively acylating N-alkyl- 1,3-diaminopropanes. In the process a N-alkyl 1,3-aminopropane is reacted with an aldebyde to form a hexahydropyrimidine, the hexahydropyrimidine is acylated and the acylated hexahydropyrimidine is then hydrolysed to give the product.

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