Substituted 1,3-diaryl-2-imino-imidazolidines and 2-...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/44 (2006.01) C07D 233/46 (2006.01) C07D 233/48 (2006.01) C07D 233/52 (2006.01) C07D 233/88 (2006.01) C07D 239/12 (2006.01) C07D 239/14 (2006.01) C07D 239/18 (2006.01) C07D 247/02 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1110626

ABSTRACT OF THE DISCLOSURE The invention relates to new compounds of the general formula (I), Image wherein R1 and R5 each represent a phenyl group, optionally substituted, R2 stands for hydrogen, formyl group, carboxy group, lower alkoxy- carbonyl group, hydroxy-(lower)-alkoxycarbonyl group, or a lower alkyl group, optionally substituted, R3 and R4 each represent. hydrogen atom or a lower alkyl group, or R2 and R3 form together an oxo or a methylene group, R6 stands for hydrogen atom, cyano group, a lower alkyl group, optionally substituted, a carbamoyl, thiocarbamoyl or amidino group, optionally substituted, or a group of the general formula R7-CO- or R8-SO 2-, and n is equal to 0 or 1, with the proviso that when R1 and R5 each represent a phenyl group and n is equal to zero, R2 and R3 may not stand for hydrogen and they may not form together an oxo group, either. These compounds possess valuable biological properties, and can be applied primarily as antiphlogistic or diuretic agents.

325989

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