Substituted 1,3-dioxanes useful as ppar modulators

Details Substituted 1,3-dioxanes useful as ppar modulators Substituted 1,3-dioxanes useful as ppar modulators

C - Chemistry, Metallurgy

07

D

C07D 319/06 (2006.01) A61K 31/357 (2006.01) A61P 3/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2676435

Specifically useful stereoisomers of 1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections as well as their use in the treatment of a disease related to TP, such as cardiovascular diseases.

L'invention concerne des stéréoisomères spécifiquement utiles de dérivés 1,3-dioxane et leur utilisation dans le traitement d'une maladie ou d'un trouble dépendant de la modulation PPAR, tel que le diabète, le cancer, une inflammation, des troubles neurodégénératifs et des infections, ainsi que leur utilisation dans le traitement d'une maladie associée à au récepteur thromboxane (TP), telle que des maladies cardiovasculaires.

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