Substituted 1-(4-aminophenyl)pyrazoles and their use as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/14 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2332957

1-(4-aminophenyl)pyrazoles optionally substituted on the 3- and 5-positions of the pyrazole ring and on the amino group at the 4-position of the phenyl ring are disclosed and described, which pyrazoles inhibit IL-2 production in T- lymphocytes.

L'invention concerne des 1-(4-aminophényl) pyrazoles éventuellement substitués dans les positions 3- et 5- du cycle pyrazole et dans le groupe aminé en position 4- du cycle phényle, ces pyrazoles inhibant la production de Il-2 par les lymphocytes T.

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