C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 223/20 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2310748
The present invention provides substituted 11-phenyl-dibenzazepine compounds which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.
Cette invention se rapporte à des composés de 11-phényl-dibenzazépine substitués qui constituent des inhibiteurs spécifiques, puissants et sûrs contre la prolifération de cellules mammaliennes. Ces composés peuvent servir à inhiber la prolifération de cellules mammaliennes in situ, dans une approche thérapeutique de traitement ou de prévention des maladies se caractérisant par une prolifération de cellules étrangères, telles que le cancer.
Bellott Emile M. Jr.
Brugnara Carlo
Clifford John J.
Fluckiger Rudolf
Gao Ying-Duo
Children's Medical Center Corporation
Mbm Intellectual Property Law Llp
Nuchem Pharmaceuticals Inc.
President And Fellows Of Harvard College
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