Substituted...

Details Substituted... Substituted...

C - Chemistry, Metallurgy

07

C

C07C 205/45 (2006.01) A61K 31/12 (2006.01) A61K 31/36 (2006.01) A61P 25/00 (2006.01) C07D 317/54 (2006.01)

Patent

CA 2292968

New compounds of formula I are described (see formula I) The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders, where a reduction in the O-methylation of catecholamines may be of therapeutical benefit, such as Parkinson's disease and parkinsonian disorders, gastrointestinal disturbances, edema formation states and hypertension.

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