C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/167 (2006.01) A61K 31/7076 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2710151
The present invention provides substituted 4-{3-[6-amino-9-(3,4-dihydroxy- tetrahydro-furan-2-yl)-9H-purin-2-yl]- prop-2-ynyl}-piperidine-1-carboxylic acid esters and pharmaceutical compositions containg the same that are selective agonists of A2A adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
La présente invention concerne des esters d'acide 4-{3-[6-amino-9-(3,4-dihydroxy-tétrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-pipéridine-1-carboxylique substitués et des compositions pharmaceutiques contenant ceux-ci qui sont des agonistes sélectifs de récepteurs d'adénosine (AR) A2A. Ces composés et compositions sont utiles en tant qu'agents pharmaceutiques.
Beauglehole Anthony
Rieger Jayson
Schmidtmann Frank
Thompson Robert
Borden Ladner Gervais Llp
Pgxhealth Llc
Trovis Pharmaceuticals Llc
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