Substituted 1h-pyrazolo[3,4-d]pyrimidine-6-amine compounds

Details Substituted 1h-pyrazolo[3,4-d]pyrimidine-6-amine compounds Substituted 1h-pyrazolo[3,4-d]pyrimidine-6-amine compounds

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61K 35/00 (2006.01)

Patent

CA 2748174

The present invention relates to substituted 1H-pyrazolo-[3,4-d]pyrimidine-6- amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.

La présente invention porte sur des composés de 1H-pyrazolo-[3,4-d]pyrimidine-6-amines substituées et sur des procédés de synthèse de ces composés. La présente invention porte également sur des compositions pharmaceutiques contenant des composés de 1H-pyrazolo-[3,4-d]pyrimidine-6-amines substituées et sur des méthodes de traitement de troubles de la prolifération cellulaire, tels que le cancer, par l'administration de ces composés et de ces compositions pharmaceutiques à des sujets en ayant besoin.

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