C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4035 (2006.01) A61K 31/4427 (2006.01) A61K 31/47 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2534570
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
La présente invention concerne des composés sélectionnés qui sont efficaces pour la prophylaxie et le traitement de maladies telles que des maladies induites par l'angiogenèse. Cette invention concerne de nouveaux composés, des analogues, des promédicaments et des sels de ceux-ci répondant aux normes pharmaceutiques, des compositions pharmaceutiques et des techniques de prophylaxie et de traitement de maladies et d'autre de pathologies impliquant des cancers et des maladies similaires. Cette invention concerne aussi des processus de fabrication de ces composés ainsi que des intermédiaires utiles dans ces processus.
Adams Jeffrey A.
Askew Benny C. Jr.
Croghan Michael
Elbaum Daniel
Germain Julie
Amgen Inc.
Gowling Lafleur Henderson Llp
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