Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives...

Details Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives... Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2671614

This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.

L'invention concerne des composés nouveaux de 2,3-dihydroimidazo[1,2-c]quinazoline, des compositions pharmaceutiques contenant de tels composés et l'utilisation de ces composés ou compositions pour l'inhibition de la phosphotidylinositol-3-kinase (PI3K) et le traitement de maladies associées à l'activité de la phosphotidylinositol-3-kinase (PI3K), en particulier pour le traitement de troubles hyperlifératifs et/ou de l'angiogenèse, en tant qu'agent unique ou en combinaison avec d'autres ingrédients actifs.

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