Substituted 2-amino tetralins and processes for synthesis

Details Substituted 2-amino tetralins and processes for synthesis Substituted 2-amino tetralins and processes for synthesis

C - Chemistry, Metallurgy

07

D

167/179, 260/295

C07D 333/20 (2006.01) C07D 307/52 (2006.01) C07C 91/23 (1985.01)

Patent

CA 1248537

-23- SUBSTITUTED 2-AMINOTETRALINS AND PROCESSES FOR SYNTHESIS ABSTRACT OF THE DISCLOSURE Novel compounds and processes for preparation of such compounds, which are useful as dopamine receptor agonists for the treatment of various diseases of the central nervous system such as Parkinson's disease and related disorders, having the structural formula Image where R2, R3 and R4 are each selected from the groups consisting of H, and OA; A is H or -?-R5; R5 is selected from the group consisting of alkyl and aromatic residues; n is 2 or 3; R1 is selected from the group consisitng of 3-pyridyl, 4-pyridyl, Image

454789

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