Substituted 2-aminotetralins

Details Substituted 2-aminotetralins Substituted 2-aminotetralins

C - Chemistry, Metallurgy

07

C

C07C 215/44 (2006.01) A61K 31/135 (2006.01) A61K 31/33 (2006.01) C07C 215/64 (2006.01) C07C 215/70 (2006.01) C07C 217/16 (2006.01) C07C 217/52 (2006.01) C07C 217/74 (2006.01) C07D 209/32 (2006.01) C07D 213/63 (2006.01) C07D 233/70 (2006.01) C07D 307/58 (2006.01) C07D 307/88 (2006.01) C07D 333/32 (2006.01) C07D 333/64 (2006.01)

Patent

CA 2065450

2065450 9100727 PCTABS00003 Optically active or racemic compounds are provided having formula (I). Wherein the radicals R1, R2, R3, R4, R6, X and N are defined in the specification. These compounds are optically active or racemic mixtures capable of binding selectively one or more dopamine D2 receptors, for instance in humans. They are useful in treatment of disorders of the central nervous, cardiovascular, and endocrine systems such as elevated intraocular pressure, schizophrenia and parkinsonism, and for inducing anorexia and weight loss in humans and other mammals.

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