Substituted 2-aminotetralins

Details Substituted 2-aminotetralins Substituted 2-aminotetralins

C - Chemistry, Metallurgy

07

C

C07C 217/06 (2006.01) A61K 31/135 (2006.01) A61K 31/22 (2006.01) A61K 31/27 (2006.01) A61K 31/335 (2006.01) C07C 217/08 (2006.01) C07C 217/12 (2006.01) C07C 219/26 (2006.01) C07C 271/44 (2006.01) C07D 305/06 (2006.01) C07D 307/14 (2006.01) C07D 309/04 (2006.01) C07D 309/06 (2006.01) C07D 317/70 (2006.01)

Patent

CA 2168097

Optically active or racemic compounds represented by formula (1] wherein R1, R2, R3, R5 and n are defined as in the specification, and pharmaceutically ac- ceptable salts thereof. These compounds are useful for alleviating Parkinsonism, glaucoma, hyperprolactinemia and for inducing weight loss in mammals.

Composés optiquement actifs ou racémiques représentés par la formule (I), dans laquelle R1, R2, R3, R5 et n sont comme définis dans la description de l'invention, et leurs sels pharmaceutiquement acceptables. Ces composés sont efficaces pour soulager la maladie de Parkinson, le glaucome, l'hyperprolactinémie, ainsi que pour provoquer la perte de poids chez les mammifères.

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