C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/222, 260/263
C07D 417/12 (2006.01) A61K 31/505 (2006.01) C07C 45/00 (2006.01) C07C 45/63 (2006.01) C07C 49/80 (2006.01) C07C 49/84 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2001168
Antimycotically active 2-aminothiazoles have been found having the formula (see formula I) in which R1 represents hydrogen or alkyl and R2 represents optionally substituted cyclohexyl or phenyl which is substituted by halogen, alkyl, halogenoalkyl, halogenoalkoxy, dioxyhalogenoalkyl or halogenoalkylthio, and their physiologically tolerable acid addition salts, - with the exception of the compounds 4-(4-chloro phenyl)-2-(2-(1,4,5,6-tetrahydropyrimidinyl)-amino, thiazole and 4-(2,4-dichlorophenyl)-2-(2-(1,4,5,6 tetrahydropyrimidinyl)-amino)-thiazole and 4-(4- - chloro-2-methylphenyl)-2-(2-(1,4,5,6-tetrahydro- pyrimidinyl)-amino)-thiazole and with the exception of the physiologically tolerable acid addition salts of these compounds - have been found.
Baasner Bernd
Ippen Joachim
Schaller Klaus
von Bittera Miklos
Aktiengesellschaft Bayer
Ridout & Maybee Llp
York Pharma Plc
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