Substituted 2-aryl-3-(heteroaryl)-imidazo[1,2-a]pyrimidines,...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2361139

This invention relates to a series of imidazopyrimidines of Formula (I), and pharmaceutical compositions containing them. The compounds of the invention inhibit the production of a number of inflammatory cytokines and are useful in the treatment and prevention of diseases associated with the overproduction thereof.

La présente invention concerne une série d'imidazopyrimidines de formule (I), et des compositions pharmaceutiques les contenant. Les composés selon la présente invention inhibent la production d'un certain nombre de cytokines inflammatoires et sont utiles dans le traitement et la prophylaxie de maladies associées à une production trop abondante desdites cytokines.

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