Substituted 2-arylimino heterocycles and compositions...

C - Chemistry – Metallurgy – 07 – D

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C07D 277/18 (2006.01) A61K 31/4164 (2006.01) A61K 31/421 (2006.01) A61K 31/423 (2006.01) A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/428 (2006.01) A61K 31/429 (2006.01) A61K 31/437 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) A61P 5/00 (2006.01) A61P 5/24 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 13/00 (2006.01) A61P 15/00 (2006.01) A61P 15/04 (2006.01) A61P 15/08 (2006.01) A61P 15/10 (2006.01) A61P 15/16 (2006.01) A61P 15/18 (2006.01) A61P 17/00 (2006.01) A

Patent

CA 2359562

This invention relates to 2-arylimino heterocycles, including 2-arylimino-1, 3- thiazolidines, 2-arylimino-2, 3, 4, 5-tetrahydro-1, 3-thiazines, 2-arylimino- 1, 3-thiazolidin-4-ones, 2-arylimino-1, 3-thiazolidin-5-ones, and 2-arylimino- 1, 3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.

La présente invention concerne des hétérocycles 2-arylimino, notamment des 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tétrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidine-4-ones, 2-arylimino-1,3-thiazolidine-5-ones, et 2-arylimino-1,3-oxazolidines, leur utilisation dans la modulation des processus induits par les récepteurs de progestérone, et des compositions pharmaceutiques utilisables dans ces thérapies.

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