Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid...

Details Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid... Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/38 (2006.01) A61K 31/435 (2006.01) A61K 31/4365 (2006.01) A61P 29/00 (2006.01) C07D 221/00 (2006.01) C07D 333/00 (2006.01)

Patent

CA 2483890

Disclosed are compounds of formula (I), wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the I.kappa.B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

La présente invention concerne des composés représentés par la formule (I), dans laquelle R¿1? et R¿2? sont tels que définis dans les spécifications. Ces composés conviennent comme inhibiteurs de l'activité kinase du complexe kinase I?B (IKK). Ces composés conviennent, par conséquent, dans le traitement des maladies induites par IKK comprenant des maladies auto-immunes, des maladies inflammatoires et le cancer. Cette invention concerne aussi des compositions pharmaceutiques comprenant ces composés et des processus de préparation de ces composés.

Affiliated with

Also associated with

Rating

Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1703131