Substituted 3-aminoquinuclidines

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 453/02 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2109415

Compounds of formula (I), wherein W, Ar1, Ar2 and Ar3 are defined as below; and the pharmaceutically acceptable salts of such compounds. These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.

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