Substituted 3-aminosydnone imines, process for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 271/04 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2060030

23233-260 ABSTRACT Novel 3-aminosydnone imines of the general formula Image (I) and the pharmacologically acceptable acid addition salts thereof, in which R1 is a C1-C6 alkyl, R2 is hydrogen or the radical -COR3, in which R3 is, for example, a C1-C4-alkyl. The compounds of formula I and their acid addition salts have valuable pharma- cological properties. They have a particularly pronounced action on the cardiovascular system and, compared with known similar compounds, have a considerably longer duration of action. They are useful for controlling and preventing cardiovascular diseases.

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