Substituted 4-(((2-thienyl)methyl)amino) benzoic acids and a...

C - Chemistry – Metallurgy – 07 – D

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260/329.3

C07D 333/28 (2006.01)

Patent

CA 1108159

ABSTRACT The invention relates to novel substituted 4-(2- -thienylmethylamino)-benzoic acid compounds, a hypolipidemic composition containing same, and a process for preparing the compounds. The compounds correspond to the formula Image wherein R is hydrogen or C1-3 alkyl, and X, Y, and Z independently represent hydrogen, chloro, or bromo, with the proviso that at least one of X, Y, and Z is chloro or bromo, and pharmaceutically acceptable salts thereof. The compounds are useful for lowering serum lipid levels in mammals. 18,307-F

300577

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