Substituted 4,5,6,7-tetrahydrothienopyridines as kcnq2/3...

Details Substituted 4,5,6,7-tetrahydrothienopyridines as kcnq2/3... Substituted 4,5,6,7-tetrahydrothienopyridines as kcnq2/3...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61P 25/04 (2006.01) A61P 25/08 (2006.01)

Patent

CA 2739740

The invention relates to substituted tetrahydrothienopyridines, to processes for their preparation, to medicaments comprising these compounds and to the use of these compounds in the preparation of medicaments.

L'invention porte sur des tétrahydrothiénopyridines substituées de formule générale (1), des procédés pour les préparer, des médicaments contenant ces composés, ainsi que l'utilisation de ces composés pour préparer des médicaments destinés au traitement de la douleur, de l'épilepsie, de l'incontinence urinaire, des états d'angoisse, de la dépendance, de la manie, des troubles bipolaires, de la migraine, des maladies cognitives, des dyskinésies associées à une dystonie et/ou de l'incontinence urinaire, où A1 est S, A2 est CR14 et A3 est CR15 ; ou A1 est CR13, et A2 est S et A3 est CR15 ; ou A1 est CR13, A2 est CR14 et A3 est S.

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