C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/72 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 213/74 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2052433
The present invention relates to compounds of the formula I (see formula I) where R1 is hydrogen or loweralkyl; R2 is hydrogen, loweralkyl, cycloalkyl, arylloweralkyl,loweralkylcarbanyl or loweralkoxycarbonyl; or alternatively the group (see formula II) as whole is (see formula III, IV, V, VI, VII or VIII) wherein R4 is loweralkyl and R5 is loweralkyl, cycloalkyl or arylloweralkyl; and R3 is hydrogen, (see formula IX, X, XI or Image ; wherein R6 is hydrogen, loweralkyl or phenyl, and R7 is hydrogen or loweralkyl, with the proviso that R1, R2 and R3 may not all be hydrogen, which compounds ace useful for alleviating memory dysfunctions characterized by a cholinergic deficit. The invention relates further to a process far the preparation of the compounds of the invention.
Hrib Nicholas Joseph
Jurcak John Gerard
Kapples Kevin James
Shutske Gregory Michael
Tomer John Dick
Aventis Pharmaceuticals Inc.
Bereskin & Parr
Hoechst-Roussel Pharmaceuticals Inc.
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