Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as...

Details Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as... Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as...

C - Chemistry, Metallurgy

07

C

C07C 323/56 (2006.01) A61K 31/19 (2006.01) A61K 31/40 (2006.01) C07C 59/48 (2006.01) C07C 59/56 (2006.01) C07C 59/64 (2006.01) C07C 59/66 (2006.01) C07C 235/42 (2006.01) C07C 235/84 (2006.01) C07C 271/22 (2006.01) C07C 323/61 (2006.01) C07C 323/62 (2006.01) C07D 209/48 (2006.01)

Patent

CA 2268770

Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have generalized formula (I) in which T is a pharmaceutically acceptable substituent group; A is CH2, CH, or N; G is CH2 or CH; and R1 is any of a variety of disclosed substituent groups. The class of compounds of the invention includes ring-containing materials in which the units A and G are joined. The compounds of the invention are mixtures of diastereomers, or individual diastereomers making up these mixtures.

L'invention concerne des inhibiteurs de métalloprotéases matricielles, des compositions pharmaceutiques les contenant, et leur procédé d'utilisation pour traiter une variété d'états physiologiques. Les composés de l'invention sont représentés par la formule générale (I), dans laquelle T représente un substituant pharmaceutiquement acceptable; A représente CH2, CH, ou N; G représente CH2 ou CH; et R<1> représente une variété quelconque des substituants de l'invention. La catégorie des composés de l'invention comprend des matériaux contenant des noyaux, dans lesquels les motifs A et G sont liés. Les composés de l'invention sont des mélanges de diastéréomères, ou des diastéréomères individuels formant ces mélanges.

Affiliated with

Also associated with

Rating

Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1686559