Substituted 4-phenyltetrahydroisoquinolines, method for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 217/22 (2006.01) A61K 31/47 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2580924

The invention relates to compounds of formula (I) in which R1 to R10 have the meanings as described in the claims. Medicaments containing compounds of this type are useful in preventing or treating various diseases. The compounds can be used, among other things, for renal diseases such as acute or chronic renal failure, for defects of biliary function, for breathing disturbances such as snoring or sleep apnea or for stroke.

L'invention concerne des composés de formule (I), dans laquelle R1 à R10 ont les significations restituées dans les revendications. Des médicaments contenant ces composés sont efficaces dans la prévention ou le traitement de diverses pathologies. Lesdits composés s'utilisent entre autres dans des maladies des reins, comme l'insuffisance rénale aiguë ou chronique, dans des troubles de la fonction biliaire, dans des troubles respiratoires comme les ronflements ou l'apnée du sommeil ou en cas d'accident vasculaire cérébral.

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