C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/10 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 471/10 (2006.01)
Patent
CA 2748491
The present invention relates to substituted 5,6-dihydro-6- phenylbenzo[f]isoquinolin-2-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2- amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
La présente invention porte sur des composés de 5,6-dihydro-6-phénylbenzo[f]isoquinoléine-2-amines substituées et sur des procédés de synthèse de ces composés. La présente invention porte également sur des compositions pharmaceutiques contenant des composés de 5,6-dihydro-6-phénylbenzo[f]isoquinoléine-2-amines substituées et sur des méthodes de traitement de troubles de la prolifération cellulaire, tels que le cancer, par l'administration de ces composés et de ces compositions pharmaceutiques à des sujets en ayant besoin.
Ali Syed M.
Ashwell Mark
Eathiraj Sudharshan
Kelleher Eugene
Lapierre Jean-Marc
Arqule Inc.
Ridout & Maybee Llp
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