Substituted 5-membered polycyclic compounds useful for...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/00 (2006.01) C07C 257/18 (2006.01) C07D 207/32 (2006.01) C07D 207/46 (2006.01) C07D 211/56 (2006.01) C07D 211/98 (2006.01) C07D 213/74 (2006.01) C07D 231/38 (2006.01) C07D 231/48 (2006.01) C07D 237/04 (2006.01) C07D 239/10 (2006.01) C07D 239/22 (2006.01) C07D 241/04 (2006.01) C07D 241/20 (2006.01) C07D 249/14 (2006.01) C07D 253/06 (2006.01) C07D 253/075 (2006.01) C07D 263/48 (2006.01) C07D 265/02 (2006.01) C07D 277/42 (2006.01) C07D 307/22 (2006.01) C07D 333/36 (2006.01) C07D 401/12 (2006.01) C07D

Patent

CA 2462645

The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.

Cette invention se rapporte à des composés et à des promédicaments de ces composés, à des compositions et à des procédés utiles pour empêcher et traiter les états thrombotiques chez des mammifères. Ces composés et ces promédicaments inhibent sélectivement certaines protéases de la cascade de réactions dans la coagulation sanguine.

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