Substituted 5h-pyrimido[5,4-b]indoles, processes for the...

Details Substituted 5h-pyrimido[5,4-b]indoles, processes for the... Substituted 5h-pyrimido[5,4-b]indoles, processes for the...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01)

Patent

CA 2673384

The invention relates to compounds of the general formula (I), methods for the production thereof, pharmaceutical preparations comprising said compounds and/or physiologically compatible salts and/or solvates that can be produced therefrom, and to the pharmaceutical use of such compounds, and the salts or solvates thereof, as inducers of apoptosis for non-solid malignant tumors of the blood-producing system, particularly for leukemia and lymphomas, particularly for leukemic B lymphocytes.

L'invention concerne des composés de formule générale (I), des procédés pour leur fabrication, des préparations pharmaceutiques qui contiennent ces composés et/ou des sels et/ou des solvates physiologiquement compatibles pouvant être fabriqués à partir de ces composés. L'invention concerne également l'utilisation pharmaceutique de ces composés, de leurs sels ou de leurs solvates comme inducteurs de l'apoptose pour des tumeurs malignes non solides du système sanguin, notamment pour des leucémies et des lymphomes, tout particulièrement pour des lymphocytes leucémiques B.

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