Substituted 6,7-dihydroimidazo(1,5,4-ef) (1,5)...

Details Substituted 6,7-dihydroimidazo(1,5,4-ef) (1,5)... Substituted 6,7-dihydroimidazo(1,5,4-ef) (1,5)...

C - Chemistry, Metallurgy

07

D

C07D 519/00 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2091057

2091057 9204354 PCTABS00011 Platelet activating factor antagonists of formula (I), wherein R1 is H or C1-C4 alkyl optionally substituted by a substituent selected from phenyl, halophenyl, pyridyl, (C1-C4 alkoxy) carbonyl and di-(C1-C4 alkyl) amino, or is C2-C4 alkyl substituted by hydroxyl or by one ore two C1-C4 alkoxy groups or is (CH2)nCONR7R8 where n is an integer from 1 to 4 and R7 and R8 are each independently H or C1-C4 alkyl, R2 is selected from H, OH and C1-C4 alkyl, R3 is selected from halo and C1-C4 alkyl, R4 is methyl, and p is an integer from 0 to 3 and m is an integer from 0 to 3; or a pharmaceutically acceptable salt thereof.

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