Substituted 6-anilinopurine derivatives as inhibitors of...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/06 (2006.01) A01N 43/90 (2006.01) A01P 21/00 (2006.01) A61K 8/49 (2006.01) A61K 31/52 (2006.01) A61P 37/06 (2006.01) A61Q 19/08 (2006.01) C12N 9/99 (2006.01)

Patent

CA 2691625

The invention relates to substituted 6-anilinopurine derivatives of the general formula I, wherein R denotes one to five substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino, alkyloxy and alkyl group, and R2 denotes amino, halogen, nitro, thio, alkylthio or alkyl group for use as inhibitors of cytokinin oxidase/dehydrogenase. The invention also relates to the compositions containing these derivatives.

L'invention se rapporte à des dérivés de 6-anilinopurine substituée de formule générale I, dans laquelle R désigne un à cinq substituants choisis indépendamment dans le groupe composé de l'hydrogène, d'un halogène, d'un groupe hydroxyle, amino, alkyloxy et alkyle et R2 désigne un groupe amino, un halogène, un groupe nitro, thio, alkylthio ou alkyle, lesdits dérivés étant destinés à être utilisés comme inhibiteurs de la cytokinine oxydase/déshydrogénase. L'invention se rapporte également aux compositions contenant ces dérivés.

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